Biodosimetry Techniques to Support a Radiological/Nuclear Response - Illustration

Assays

• DCA: dicentric chromosome analysis
• PCC: premature chromosomal condensation
• γ-H2AX: sensitive molecular marker of DNA double strand breaks
• EPR: electronic paramagnetic resonance
• LDR: lymphocyte depletion rate/kinetics
• miRNA: microsomal RNA; mRNA: messenger RNA
• MN-BE: micronucleus assay in exfoliated buccal epithelial cells
• CBMN: cytokinesis-block micronucleus technique

Source of graphic above: Balajee Adayabalam, Ph.D. (Technical Director of Cytogenetic Biodosimetry Laboratory (REAC/TS/ORISE, ORAU), 2021