Public Health Emergency Researchers:
Information for Radiation Emergencies
- Public Health Emergency Research
- National Health Security Preparedness Index
- HHS/ASPR Public Health Emergency Research Initiatives
- See also: Data Elements to Collect During Radiation Emergencies
Public Health Emergency Research
- Lurie N, Keusch GT, Dzau VJ. Urgent lessons from COVID 19: why the world needs a standing, coordinated system and sustainable financing for global research and development. Lancet. 2021 Mar 27;397(10280):1229-1236. [PubMed Citation]
- Understanding and improving medical preparedness and response during mass casualty incidents is an increasingly important area of research.
- Involves applying scientific processes to development of public policy, protecting public health, studying and enhancing responder safety and health, and environmental issues related to assessment, protection, and remediation.
- Selected articles and references on this page noted below are relevant to
- Establishing and evaluating benchmarks for preparedness
- Learning from actual incidents
- Preparedness and responses generally, not radiation incidents specifically.
- Long-Term Health Monitoring of Populations Following a Nuclear or Radiological Incident in the United States, Proceedings of a Workshop (NASEM, 2019)
- Reviews the process for preparing a radiation registry for monitoring long-term health effects of populations affected by a nuclear or radiological incident.
- Assesses existing information, useful practices, and tools for planning a radiation registry that will enhance incident monitoring and response methods.
- A Framework for Assessing Mortality and Morbidity after Large-Scale Disasters, Consensus Study Report (NASEM, 2020)
- Reviews and describes the current state of the field of disaster-related mortality and significant morbidity assessment.
- Examines practices and methods for data collection, recording, sharing, and use across state, local, tribal, and territorial stakeholders; evaluates best practices.
- Identifies areas for future resource investment.
National Health Security Preparedness Index (NHSPI)
- Launched in 2013, it is "the most comprehensive measure of the nation's health security preparedness to date".
- Uses primarily existing (already collected), public-use, public health and health care system measures and compares these data against key national standards for preparedness.
- Index evaluations by state
- Recent publications
- Uzun Jacobson E, Inglesby T, Khan AS, Rajotte JC, Burhans RL, Slemp CC, Links JM. Design of the national health security preparedness index. Biosecur Bioterror. 2014 May-Jun;12(3):122-31. [PubMed Citation]
- Lumpkin JR, Miller YK, Inglesby T, Links JM, Schwartz AT, Slemp CC, Burhans RL, Blumenstock J, Khan AS. The importance of establishing a national health security preparedness index. Biosecur Bioterror. 2013 Mar;11(1):81-7. [PubMed Citation]
- Additions to this bibliography will appear in future updates to REMM.
HHS/ASPR Public Health Emergency Research Initiative
- Science Preparedness (HHS/ASPR) — Scientific research framework that can enable emergency planners, responders and the whole community to better prepare for, respond to, and recover from major public health emergencies
- Public Health Emergency Research Review Board (PDF - 1.6 MB) (PHERRB, 2012, see pages 87, 115)
- Serves as IRB of record by conducting expedited human subject protection review for proposed public health emergency research studies
- Supplements the review from local institutions by providing regulatory review
- NIH designated to maintain PHERRB infrastructure withinin the Office of Human Subjects Research Protection (OHSRP)
- Protocols are usually multisite studies
- Created partnership with Institute of Medicine to convene meetings quickly to assess research opportunities during responses to disasters or outbreaks (See below.)
- Sponsored workshops and Exercises
- Call to Action: include scientific investigations as an integral component of disaster planning and response (PDF - 368 KB) (April 2011)
- ASPR Scientific Preparedness and Response for Public Health Emergencies Workshop (PDF - 194 KB) (Sept 2012)
- Strengthening the Disaster Resilience of the Academic Biomedical Research Community: Protecting the Nation’s Investment (National Academies of Sciences, Engineering, and Medicine, 2017)
- The Next Generation of Biomedical and Behavioral Sciences Researchers: Breaking Through: Consensus Study Report (National Academies of Sciences, Engineering, and Medicine, 2018)
- Single IRB Policy for Multi-site Research: NIH guidelines
- Learn about policy expectations for the use of single IRBs for multi-site grant applications
- Coleman, C., Bader, J., Koerner, J., Hrdina, C., et al. Chemical, Biological, Radiological, Nuclear, and Explosive (CBRNE) Science and the CBRNE Science Medical Operations Science Support Expert (CMOSSE). Disaster Med Public Health Prep. 2019 Jun 17:1-16. [PubMed Citation]
- Lurie N, Manolio T, Patterson AP, Collins F, Frieden T. Research as a part of public health emergency response. N Engl J Med. 2013 Mar 28;368(13):1251-5. [PubMed Citation]
- Disaster Information Management Research Center (DIMRC) (NIH/NLM)
- WHO Guidance on Research Methods for Health and Disaster Risk Management (WHO 2018-2022 implementation)
- Sendai Framework for Disaster Risk Reduction 2015-2020 (WHO, 2015)
- WHO Technical Guidance Notes on Sendai Framework Reporting for Ministries of Health (WHO, Nov 2020)
- Hazard Definition and Classification Review (WHO/UNDRR, 2020)
- Health Emergency and Disaster Risk Management Framework (WHO, 2019)
- Ethics in Epidemics, Emergencies and Disasters: Research, Surveillance and Patient Care (WHO, 2015)
- UN Office for Disaster Risk Reduction (WHO/UNDRR)
- Building a National Capability to Monitor and Assess Medical Countermeasure Use during a Public Health Emergency, Going Beyond the Last Mile (Proceedings of a Workshop, National Academy of Science, 2017)
- Methodologies for Evaluating and Grading Evidence: Considerations for Public Health Emergency Preparedness and Response: Proceedings of a Workshop—in Brief (NASEM, 2019)
- Murphy DJ, Rubinson L, Blum J, Isakov A, Bhagwanjee S, Cairns CB, Cobb JP, Sevransky JE; United States Critical Illness and Injury Trials Group - Program for Emergency Preparedness. Development of a Core Clinical Dataset to Characterize Serious Illness, Injuries, and Resource Requirements for Acute Medical Responses to Public Health Emergencies. Crit Care Med. 2015 Nov;43(11):2403-8. [PubMed Citation]
- Piltch-Loeb R, Kraemer JD, Nelson C, Stoto MA. A public health emergency preparedness critical incident registry. Biosecur Bioterror. 2014 May-Jun;12(3):132-43. [PubMed Citation]
- Savoia E, Preston J, Biddinger PD. A Consensus Process on the Use of Exercises and After Action Reports to Assess and Improve Public Health Emergency Preparedness and Response. Prehosp Disaster Med. 2013 Mar 28:1-3. [PubMed Citation]
- Engaging the Public in Critical Disaster Planning and Decision Making. (Institute of Medicine, August 23, 2013)
- Decker JA, Kiefer M, Reissman DB, Funk R, Halpin J, Bernard B, Ehrenberg RL, Schuler CR, Whelan E, Myers K, Howard J. A decision process for determining whether to conduct responder health research following large disasters. Am J Disaster Med. 2013 Winter;8(1):25-33. [PubMed Citation]
- Chan JL, Burkle FM Jr. A framework and methodology for navigating disaster and global health in crisis literature. PLoS Curr. 2013 Apr 4;5. [PubMed Citation]
- Roy N, Thakkar P, Shah H. Developing-world disaster research: present evidence and future priorities. Disaster Med Public Health Prep. 2011 Jun;5(2):112-6. [PubMed Citation]
- A National Agenda for Public Health Systems Research on Emergency Preparedness. RAND Corporation, Technical Report 660.
- Public Health Preparedness and Response to Chemical and Radiological Incidents, Functions, Practices and Areas for Future Work. RAND Corporation, Technical report 719.